|Viking Genes: Viking Health Study Shetland
|Viking Health Study Shetland
|Viking Health Study Shetland is a cohort of volunteers with ancestry from the Shetland Isles, primarily for identifying genetic variants influencing disease.
|#Subjects at Baseline
|There are 2,106 participants
|The University of Edinburgh
|MRC Human Genetics Unit / Usher Institute
|Principal Investigator (PI)
|Prof James F. Wilson
|Key Study References
Kerr SM, Klaric L, Halachev M et al: An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort. Sci Rep 2019; 9: 10964.
|Population Based Study?
|Family Based Study?
|Clinical based sample?
|Is there follow-up data available?
|Summary data from the EHR is available; consent was also given for recontact
|Were participants included prior to development of dementia (may refer to controls only)?
|All participants were free of dementia (to the extent of being able to attend a clinic and complete a questionnaire) at recruitment
|Were participants included prior to development of MCI (may refer to controls only)?
|As above, mild cognitive impairment is possible, but unlikely given the complexity of the recruitment process
|How is data collected?
|From clinic measurements, a paper questionnaire, from the EHR; from measurements on serum and plasma samples; also genetic data from blood or saliva samples
|Who carries out data collection?
|Recruitment is complete. The participants completed a detailed paper questionnaire and research nurses collected samples and made a wide range of measurements
|Does this take place in participants' homes or at a central location?
|In a central location in Lerwick, Shetland
|Do participants take part individually or are families/partners involved?
|Individuals, their families and partners were all welcome to join the cohort if eligible
|Dementia cases ascertained as part of study:
|How many times followed up?
|Study start date
|The year 2013
|Study end date
|The year 2015
|Is study ongoing?
|Is study still recruiting?
|Participant is aged 18 years or above, willing and able to give informed consent for participation and has at least three Shetlandic grandparents
|Lack of capacity to provide informed consent and attend clinics, or the lack of Northern Isles ancestry