Cohort Name |
Viking Genes: VIKING II Study |
Cohort Acronym |
VIKING II |
Study Overview |
The purpose of VIKING II is to create an observational cohort of volunteers with ancestry from the Northern and Western Isles of Scotland, primarily for identifying genetic variants influencing disease. |
#Subjects at Baseline |
5366 participants had completed the online study questionnaire by 21/10/2022 |
Institution Name |
The University of Edinburgh |
Department Name |
MRC Human Genetics Unit / Usher Institute |
City |
Edinburgh |
Study/Database Website |
www.ed.ac.uk/viking |
Principal Investigator (PI) |
Prof James F. Wilson |
Key Study References |
doi: https://doi.org/10.1101/2021.10.15.21265045 |
Population Based Study? |
Yes |
Family Based Study? |
Yes |
Clinical based sample? |
No |
Is there follow-up data available? |
Summary data from the EHR will be available in future; consent is also given for recontact |
Were participants included prior to development of dementia (may refer to controls only)? |
All participants were free of dementia (to the extent of being able to complete an online questionnaire) at recruitment |
Were participants included prior to development of MCI (may refer to controls only)? |
As above, mild cognitive impairment is possible, but unlikely given the complexity of the online recruitment process |
How is data collected? |
Online and from the EHR (routine NHS data on participants living in Scotland); also genetic data from saliva samples |
Who carries out data collection? |
The participants complete a detailed online questionnaire |
Does this take place in participants' homes or at a central location? |
In participants' homes |
Do participants take part individually or are families/partners involved? |
Individuals, their families and partners are all welcome to join the cohort if eligible |
Dementia cases ascertained as part of study: |
Zero |
How many times followed up? |
Zero |
Study start date |
14/01/2020 00:00:00 |
Study end date |
18/02/2023 00:00:00 |
Is study ongoing? |
Yes |
Is study still recruiting? |
Yes |
Inclusion criteria |
Participant is aged 16 years or above, willing and able to give informed consent for participation and has at least two Shetlandic, Orcadian or Hebridean grandparents |
Exclusion criteria |
Lack of capacity to provide informed consent, or the lack of Northern Isles or Hebridean ancestry, or no access to the internet |