Cohort Descriptives

Variable Response
Cohort Name Biomagnetic biomarkers for dementia
Cohort Acronym BioFIND
Study Overview Resting-state MEG data and T1 structural MRI data on ~160 MCI patients and ~160 healthy controls
#Subjects at Baseline 324
Institution Name University of Cambridge
Department Name MRC Cognition & Brain Sciences Unit
City Cambridge
Study/Database Website

Principal Investigator (PI) Richard Henson
Key Study References

Hughes, L.E., Henson, R.N., Pereda, E., Bruña, R., López-Sanz, D., Quinn, A.J., Woolrich, M.W., Nobre, K.C., Rowe, J.B., Maestú, R. & BioFIND Working Group (2019). Biomagnetic biomarkers for dementia: A pilot multicentre study with a recommended methodological framework for magnetoencephalography. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. Vaghari, D., Bruna R.,, Hughes, L., Nesbitt, D., Tibon, R., Rowe, J., Maestu, F. & Henson, R. (in prep). A multi-site, multi-participant magnetoencephalography resting-state dataset to study dementia: The BioFIND dataset.

Population Based Study? No
Family Based Study? No
Clinical based sample? Yes
Is there follow-up data available? Limited
Were participants included prior to development of dementia (may refer to controls only)? Yes
Were participants included prior to development of MCI (may refer to controls only)? Yes
How is data collected? Across several smaller studies conducted at MRC CBU in Cambridge and CTB in Madrid, Spain
Who carries out data collection? CBU and CTB
Does this take place in participants' homes or at a central location? In MEG and MRI labs at CBU and CTB
Do participants take part individually or are families/partners involved? Individually
Dementia cases ascertained as part of study:
How many times followed up? Occasionally, as part of Cambridge and Madrid Memory Clinics
Study start date 7/9/1905 12:00:00 AM
Study end date ongoing
Is study ongoing? yes
Is study still recruiting? yes
Inclusion criteria MCI or age/sex matched healthy control
Exclusion criteria not MEG or MRI compatible