Cohort Descriptives

Variable Response
Cohort Name Samsung Medical Center Amyloid PET Cohort
Cohort Acronym SMC Amyloid PET
Study Overview To verify the predictive effect of amyloid-pathology (amyloid-PET imaging) and biomarkers from the subjects who had been followed up for more than 5 years
#Subjects at Baseline 120
Institution Name SAMSUNG MEDICAL CENTER
Department Name Department of Neurology
City Seoul , Korea
Principal Investigator (PI) Sang Won Seo
Population Based Study? Yes
Family Based Study? No
Clinical based sample? Yes
Is there follow-up data available? No
Were participants included prior to development of dementia (may refer to controls only)? Yes
Were participants included prior to development of MCI (may refer to controls only)? Yes
How is data collected? In person: Data is collected at Dementia Centre in Samsung Medical Centre
Who carries out data collection? Interviewers and Clinicians: Researchers including Researching Doctor and Researcher
Does this take place in participants' homes or at a central location? Central: Samsung Medical Centre
Do participants take part individually or are families/partners involved? Individually
Dementia cases ascertained as part of study: Yes
Diagnosis based on review of existing clinical data Yes
Was diagnosis/primary outcomes made blind to exposure variables? Yes
How many times followed up? Within 1 year
How regular is follow-up? 1
Study start date 1/15/2016 12:00:00 AM
Is study ongoing? No
Is study still recruiting? No
Inclusion criteria CN (Community dwelling people ), SMI,MCI and AD (SMC clinic patients)

Administration

Sub-category Variable type Variables generally collected
Study ID Y
Age Y
Sex Y

Sociodemographic

Sub-category Variable type Variables generally collected
Age Y
Age at time of diagnosis of dementia Y
Age at last follow-up Y
Sex Y
Ethnicity Y
Years of education Y

Mental Health Status

Sub-category Variable type Variables generally collected
Geriatric Depression Scale (GDS) Y

Cognitive Status

Sub-category Variable type Variables generally collected
Dementia diagnosis Y
Alzheimer's dementia Y
MCI Y
Subjective complaint Y

Lifestyle

Sub-category Variable type Variables generally collected
Smoking Y
Pack years Y
Current smoking Y
Former smoking Y
Alcohol Y

Physical Examination

Sub-category Variable type Variables generally collected
Blood pressure Y
Weight Y
Height Y
Heart Rate Y
Blood Lipids Y

Biosample Assays

Sub-category Variable type Variables generally collected
Plasma Y
Serum Y
DNA Y

Digital Phenotyping

Sub-category Variable type Variables generally collected
Visual Memory Y
Verbal Memory Y
Language Y
Vigilance Y
Latent Memory Y
MMSE Y
Clinical Dementia Rating Scale (CDR) Y
Global Deterioration Scale (GDS) Y

Genomics

Sub-category Variable type Variables generally collected
APOE gene screening Y

Metabolomics

Sub-category Variable type Variables generally collected
Glucose Y
Lipids Y
Liver Function Tests Y
Serum creatinine Y