Cohort Descriptives

Variable Response
Cohort Name Emory Healthy Brain Study
Cohort Acronym EHBS
Study Overview The Emory Healthy Brain Study is a sub-study of the Emory Healthy Aging Study, the largest-ever clinical research study in Atlanta that seeks to better understand aging and age-related diseases. While the Emory Healthy Aging Study is an online study, participants in the Emory Healthy Brain Study will come to Emory for collection of biological specimens. To participate in the Emory Healthy Brain Study, individuals will complete a series of tests, including blood draws, a lumbar puncture to collect spinal fluid, an eye scan, and a heart and vascular assessment. Participants will also take memory tests and have a gait analysis done, which involves walking on a special mat to examine the mechanics of how they move. Those who complete the tests, typically done in a single day, will receive compensation. The study is open to generally healthy individuals ages 45-75 years old and participation is completely voluntary.
Institution Name Emory University
Department Name Emory Brain Health Center
City Atlanta, Georgia, USA
Study/Database Website

https://healthyaging.emory.edu/brain-study/

Principal Investigator (PI) Dr James Lah
Population Based Study? Yes
Family Based Study? No

Administration

Sub-category Variable type Variables generally collected
Study ID Y
Age Y
Sex Y

Sociodemographic

Sub-category Variable type Variables generally collected
Age Y
Ethnicity Y
Years of education Y
Employment status Y
Socioeconomic status measures Y

Physical Health Status

Sub-category Variable type Variables generally collected
Cardiovascular disease data Y
Myocardial infarction Y
Medication use for CVD Y
Hypertension Y
Systolic/diastolic BP Y
Hypotension Y
Hypercholesterolemia Y
Cancer Y
Diabetic Status Y
Stroke type Y
Transient Ischemic Attack Y
Head trauma data Y
Loss of consciousness Y

Health Care Utilisation

Sub-category Variable type Variables generally collected
Medication use Y
Medication use for CVD Y

Psychological Status

Sub-category Variable type Variables generally collected
Sleep assessment Questionnaires Y
Actigraphy to measure sleep patterns Y

Cognitive Status

Sub-category Variable type Variables generally collected
Alzheimer's dementia Y
Parkinson's disease Y
MCI Y
Subjective complaint Y

Lifestyle

Sub-category Variable type Variables generally collected
Smoking Y
Pack years Y
Current smoking Y
Former smoking Y
Alcohol Y
Units per day/week vs weekend Y
Abstainers/former users Y
Binge drinking Y
Physical activity and exercise Y
Type of exercise: heavy,light Y
Exercise duration Y
Objective measures of activity Y
Diet Y
Sleep assessment Questionnaires Y
Actigraphy to measure sleep patterns Y

Physical Environment

Sub-category Variable type Variables generally collected
Blood pressure Y
Weight Y
Height Y
Visual fields (direct/indirect) Y
Colour vision Y

Physical Examination

Sub-category Variable type Variables generally collected
BMI Y
Blood lipids Y

Biosample Assays

Sub-category Variable type Variables generally collected
Plasma Y
Serum Y
RNA Y
DNA Y
Abeta 1-40 Y
Abeta 1-42 Y
CSF collected Y

Digital Phenotyping

Sub-category Variable type Variables generally collected
Verbal memory (Verbal Fluency Phonemic Test) Y
Language (Multilingual Naming Test) Y
Vigilance Y
Latent Memory Y
NART Y
MoCA Y

Genomics

Sub-category Variable type Variables generally collected
APOE gene screening Y