| Cohort Name |
The Cognitive Health in Ageing Register: Investigational, Observational, and Trial studies in dementia research |
| Cohort Acronym |
CHARIOT |
| Study Overview |
Identifying cognitively healthy people at high risk of developing dementia is an ever-increasing focus. The success of research in this area is dependent on having access to a well characterised, representative and sufficiently large population of individuals. The CHARIOT register is a primary care-based recruitment register for research into the prevention of dementia. The CHARIOT register was designed specifically to support recruitment into observational natural history studies of pre-symptomatic or prodromal dementia stages, and primary or secondary prevention pharmaceutical trials or other prevention strategies for dementia and other cognitive problems associated with ageing. |
| #Subjects at Baseline |
28000 |
| Institution Name |
Imperial College London |
| Department Name |
Neuroepidemiology and Ageing Research Unit |
| City |
London |
| Principal Investigator (PI) |
Prof Lefkos Middleton |
| Key Study References |
Please see Literature section |
| Population Based Study? |
Yes |
| Family Based Study? |
No |
| Clinical based sample? |
No |
| Is there follow-up data available? |
No |
| Were participants included prior to development of dementia (may refer to controls only)? |
Yes |
| Were participants included prior to development of MCI (may refer to controls only)? |
Yes |
| Dementia cases ascertained as part of study: |
No |
| Diagnosis based on review of existing clinical data |
No |
| Is study ongoing? |
Yes |
| Is study still recruiting? |
Yes |
| Inclusion criteria |
Aged 50-85 inclusive |
| Exclusion criteria |
Diagnosis of dementia of any type. Psychotic conditions |