Cohort Descriptives

Variable Response
Cohort Name The Cognitive Health in Ageing Register: Investigational, Observational, and Trial studies in dementia research
Cohort Acronym CHARIOT
Study Overview Identifying cognitively healthy people at high risk of developing dementia is an ever-increasing focus. The success of research in this area is dependent on having access to a well characterised, representative and sufficiently large population of individuals. The CHARIOT register is a primary care-based recruitment register for research into the prevention of dementia. The CHARIOT register was designed specifically to support recruitment into observational natural history studies of pre-symptomatic or prodromal dementia stages, and primary or secondary prevention pharmaceutical trials or other prevention strategies for dementia and other cognitive problems associated with ageing.
#Subjects at Baseline 28000
Institution Name Imperial College London
Department Name Neuroepidemiology and Ageing Research Unit
City London
Principal Investigator (PI) Prof Lefkos Middleton
Key Study References

Please see Literature section

Population Based Study? Yes
Family Based Study? No
Clinical based sample? No
Is there follow-up data available? No
Were participants included prior to development of dementia (may refer to controls only)? Yes
Were participants included prior to development of MCI (may refer to controls only)? Yes
Dementia cases ascertained as part of study: No
Diagnosis based on review of existing clinical data No
Is study ongoing? Yes
Is study still recruiting? Yes
Inclusion criteria Aged 50-85 inclusive
Exclusion criteria Diagnosis of dementia of any type. Psychotic conditions


Sub-category Variable type Variables generally collected
Study ID Y
Age Y
Sex Y


Sub-category Variable type Variables generally collected
Age Y
Sex Y
Ethnicity Y
Socioeconomic status measures (Index of Multiple Deprivation-IMD) Y