Cohort Descriptives

Variable Response
Cohort Name The Airwave Health Monitoring Study
Cohort Acronym Airwave
Study Overview The Airwave Health Monitoring Study was established to evaluate possible health risks associated with the use of TETRA, a digital communication system used by the police forces and other emergency services in Great Britain since 2001. It is a long-term observational study following up the health of the police force with respect to TETRA exposure, and ability to monitor both cancer and non-cancer health outcomes.
#Subjects at Baseline 55000
Institution Name Imperial College London
Department Name Department of Epidemiology and Biostatistics School of Public Health
City London
Study/Database Website

http://www.police-health.org.uk/

Principal Investigator (PI) Prof Paul Elliott
Key Study References

Please see the Literature tab

Population Based Study? Yes
Family Based Study? No
Clinical based sample? No
Is there follow-up data available? Yes
Were participants included prior to development of dementia (may refer to controls only)? Yes
Were participants included prior to development of MCI (may refer to controls only)? Yes
How is data collected? Combination: In the first phase, every employee receives the enrolment (paper) questionnaire via routine administration or the occupational health service. This questionnaire is scanned and data received at Imperial College.
Who carries out data collection? Interviewers. Clinical staff: Nursing staff were involved although the questionnaires were carried out themselves.
Does this take place in participants' homes or at a central location? Home Central: Paper questionnaires were sent out by each force to the home or office of employees and clinics were performed regionally.
Do participants take part individually or are families/partners involved? Individually
Dementia cases ascertained as part of study: No
Diagnosis based on review of existing clinical data No
Was diagnosis/primary outcomes made blind to exposure variables? No
How many times followed up? 2
Study start date 1/1/2004 12:00:00 AM
Is study ongoing? Yes
Is study still recruiting? No
Inclusion criteria People employed in the police force across the UK
Exclusion criteria Unable to consent.

Administration

Sub-category Variable type Variables generally collected
Study ID Y
Age Y
Sex Y

Sociodemographic

Sub-category Variable type Variables generally collected
Age Y
Age at last follow-up Y
Age at time of death Y
Sex Y
Ethnicity Y
Education Y
Employment Status Y
Socioeconomic status measures Y

Physical Health Status

Sub-category Variable type Variables generally collected
Cardiovascular disease data (flagged from linkage) Y
Myocardial infarction Y
Hypertension Y
Systolic/Diastolic BP Y
Hypercholesterolemia Y
Hypotension; Y
Cancer Y
Diabetic Status Y
Stroke data Y
Transient Ischemic Attack Y

Reproductive History

Sub-category Variable type Variables generally collected
Pregnancy Y
Menstruation Y

Health Care Utilisation

Sub-category Variable type Variables generally collected
Medication Use Y
Hospital Utilisation Y

Psychological Status

Sub-category Variable type Variables generally collected
Resilience evaluation Y
QoL scale - Job Strain (selected items from the Karasek Job content Questionnaire) Y
Sleep assessment - Fatigue (Short Checklist Individual Strength) Y

Mental Health Status

Sub-category Variable type Variables generally collected
Psychiatric evaluations Y
Anxiety measure Y

Cognitive Status

Sub-category Variable type Variables generally collected
Parkinson's Disease Y

Lifestyle

Sub-category Variable type Variables generally collected
Smoking Y
Current smoking Y
Alcohol Y
Diet Y
10 Items Food Frequency Questionnaire Y
Other dietary items Y

Physical Environment

Sub-category Variable type Variables generally collected
Living situation Y

Social Environment

Sub-category Variable type Variables generally collected
Shift work recorded as well as Hours of Sleep Y

Physical Examination

Sub-category Variable type Variables generally collected
BMI (assessed before onset of Dementia) Y
Blood pressure (assessed before onset of Dementia) Y
Weight (assessed before onset of Dementia) Y
Height (assessed before onset of Dementia) Y
Heart Rate (assessed before onset of Dementia) Y
Anthropometry (assessed before onset of Dementia) Y
ECG (assessed before onset of Dementia) Y
Spirometry (assessed before onset of Dementia) Y
Fat percentage Y
Dyslipidemia Y
Blood lipids (HDL, total cholesterol, apoA and apoB) Y
Standing height Y
Sitting height Y
Hip circumference Y
Waist circumference Y
Bio-impedance Y
Arterial stiffness Y
Pulse wave velocity Y
Short international physical activity questionnaire (IPAC) Y

Biosample Assays

Sub-category Variable type Variables generally collected
Plasma Y
Serum Y
DNA Y
RNA Y
Urine Y

Digital Phenotyping

Sub-category Variable type Variables generally collected
Attention Y
Reaction time Y
Associative learning Y
Vigilance Y
Working memory Y
Executive Function Y
Verbal reasoning Y
Numeric reasoning Y

Genomics

Variable type
This cohort collects Genomics data on: Exome chip subjects: First batch of samples was completed in April 2013. For this project, 2016 Human DNA samples were processed using the Illumina Infinium HumanExome-12v1-1 BeadChip Arrays and following the Infinium HD Assay Ultra protocol. Analysis of the second batch of samples was completed in December 2014. For this project, 14976 Human DNA samples were processed, in 52 batches of 288 samples. Samples were processed with Illumina Infinium HumanCoreExome-12v1-1 BeadChip Arrays following the Infinium HD Assay Ultra protocol.
ExomeChip versions: Illumina Infinium Human Exome 12: Illumina Infinium HumanExome-12v1-1 BeadChip Arrays. Analysis of the second batch of samples was completed in December 2014. For this project, 14976 Human DNA samples were processed, in 52 batches of 288 samples. Samples were processed with Illumina Infinium HumanCoreExome-12v1-1 BeadChip Arrays following the Infinium HD Assay Ultra protocol.
Exome/Genome sequencing broad platform categories: Illumina.

Metabolomics

Sub-category Variable type Variables generally collected
CRP (c-reactive protein) Y
Glucose Y
HbA1c Y
Serum creatinine Y
Lipids (HDL, total cholesterol, apoA and apoB) Y
Liver Function Tests (In a subsample) Y